A novel role for SALL4 during scar-free wound healing in axolotl
نویسندگان
چکیده
منابع مشابه
Wound healing--scar wars.
Scafring following wounding is a major medical problem. In skin wounds or bums scarring often leads to adverse cosmesis and consequent psychological problems, adverse function particularly over joints and retardation of growth especially in children. Scarring in muscle adversely affects movement and can cause ankylosis. In abdominal and pelvic organs scarring can lead to life threatening strict...
متن کاملassessment of the effect of honey as a topical therapy for intra oral wound healing in rat.
چکیده ندارد.
15 صفحه اولMast Cells Contribute to Scar Formation During Fetal Wound Healing
Scar formation is a potentially detrimental process of tissue restoration in adults, affecting organ form and function. During fetal development, cutaneous wounds heal without inflammation or scarring at early stages of development; however, they begin to heal with significant inflammation and scarring as the skin becomes more mature. One possible cell type that could regulate the change from s...
متن کاملScar-free healing
Mending wounds quickly while keeping them scar-free is not an impossible task. Mori et al. (page 43) find that shutting down a protein called osteopontin does the trick. Scars form when the inflammatory response that protects skin wounds against invading microbes induces the release of chemokines, which recruit fibroblasts. These cells then generate swathes of collagen to provide a new matrix f...
متن کاملScar Prevention and Enhanced Wound Healing Induced by Polydeoxyribonucleotide in a Rat Incisional Wound-Healing Model
High-mobility group box protein-1 (HMGB-1) plays a central role in the inflammatory network, and uncontrolled chronic inflammation can lead to excessive scarring. The aim of this study was to evaluate the anti-inflammatory effects of polydeoxyribonucleotide (PDRN) on scar formation. Sprague-Dawley rats (n = 30) underwent dorsal excision of the skin, followed by skin repair. PDRN (8 mg/kg) was a...
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ژورنال
عنوان ژورنال: npj Regenerative Medicine
سال: 2016
ISSN: 2057-3995
DOI: 10.1038/npjregenmed.2016.16